Vitamin K and Osteoporosis
نویسندگان
چکیده
منابع مشابه
Vitamin K nutrition and postmenopausal osteoporosis.
Editorial The key question of vitamin K nutrition in humans may be how much is enough. As with other vitamins, the answer could depend on which biological effect is observed. Vitamin K was first discovered as an antihemorrhagic factor, and it is now known to be required for the synthesis of several proteins involved in blood coagulation (prothrombin; Factors VII, IX, and X; proteins S and C). O...
متن کاملThe Role of Vitamin K in Bone Remodeling and Osteoporosis
Vitamin K is an essential fat soluble vitamin involved in the regulation of normal coagulation. However, growing evidence highlights that this molecule appears to be also implicated in the regulation of other important biological functions such as bone mineralization, calcium homeostasis, apoptosis, cell growth and signal transduction. In particular, many studies have focused their attention on...
متن کاملImportance of calcium, vitamin D and vitamin K for osteoporosis prevention and treatment.
Throughout the life cycle the skeleton requires optimum development and maintenance of its integrity to prevent fracture. Bones break because the loads placed on them exceed the ability of the bone to absorb the energy involved. It is now estimated that one in three women and one in twelve men aged >55 years will suffer from osteoporosis in their lifetime and at a cost in the UK of > 1.7 pounds...
متن کاملCombined treatment of vitamin K and teriparatide on bone metabolism and biomechanics in rats with osteoporosis
Postmenopausal osteoporosis is a degenerative disease caused by lack of estrogen whereby bone degeneration exceeds bone formation, resulting in loss of bone mass. Various drugs have been utilized in an attempt to ameliorate bone strength in such patients. The aim of the present study was to compare the effects of vitamin K or teriparatide alone and combined on bone metabolism and biomechanics i...
متن کاملVitamin K in the treatment and prevention of osteoporosis and arterial calcification.
PURPOSE The role of vitamin K in the prevention and treatment of osteoporosis and arterial calcification is examined. SUMMARY Vitamin K is essential for the activation of vitamin K-dependent proteins, which are involved not only in blood coagulation but in bone metabolism and the inhibition of arterial calcification. In humans, vitamin K is primarily a cofactor in the enzymatic reaction that ...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1995
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)46130-1